Οι πρώτες συγκεκριμένες λεπτομέρειες για το πολυαναμενόμενο Prey 2 ήρθαν στο φως της δημοσιότητας μέσω σουηδικού περιοδικού (από το Neogaf), και έχω την αίσθηση ότι θα δυσαρεστήσουν κάποιους. Το λέω αυτό κυρίως λόγω δύο συγκεκριμένων στοιχείων: πρώτον, σύμφωνα πάντα με το περιοδικό, το παιχνίδι αναπτύσσεται με βάση το Χbox 360, και δεύτερον, δεν έχει multiplayer. Ειδικά για το δεύτερο, η Human Head θεωρεί ότι λόγω του τρελού ανταγωνισμού που επικρατεί στην κατηγορία των multiplayer FPS, είναι καλύτερα να επικεντρωθεί στo single-player. Κατά τ' άλλα, ο πρωταγωνιστής του Prey 2 ονομάζεται Killian Samuels, ενώ η ανάπτυξη του παιχνιδιού ξεκίνησε πριν τρία χρόνια. Αναλυτικά όλες λεπτομέρειες παρακάτω. Το Prey 2 θα κυκλοφορήσει το 2012.

- Main character is Killian Samuels, sheriff and prison guard.
- Been in development for 3 years
- X360 main platform, PC and PS3 versions in development (as announced)
- Pretty nice graphics overall (not jaw-dropping but good), graphics style a mix of Bioshock and Mass Effect
- "Heavily inspired by Mirror's Edge, but also Mass Effect, Riddick and Blade Runner" - Producer
- Use the surroundings, big areas where you can sneak up on enemies using the shadows
- No multiplayer, 3D, Kinect or Move
- As said in the PR, 2012 release date
- Tommy/Intro spoiler:First level is basically the beginning of Prey, but instead of controlling Tommy you control Killian.
- Human head: "If the first Prey was the Luke Sywalker version of the story, Prey 2 is Bobba Fett's story".
- The project has been restarted several times
- Open game structure. "Go wherever you want, talk to whoever you want, do the missions you want".
- "Killian as flexible and limber as Faith of ME, leaping over hights, hanging by arms from pipes, balancing on thin boards and jumping like a cat upwards structures"
- "An enhanced Killzone esque cover system, battles looks so flexible, brings your thoughts back to Vanquish"
- Parkour moments when being chased by enemies
- Money can be used to upgrade your armor, weapons, but also abilities, example to make enemies hover in the air
- Human Head: "Every area is comparable to Assassin's Creed 2", whatever that means. Planet is Exodus. Desert levels, big cities, "in the wilds", cave areas
- "It has the moving scheme from Mirror's Edge, the freedom of Mass Effect and the fire fights of Killzone 2" (writer loved Prey 1)
- Different kinds of ammo, weapons can be customized/rebuilt
- Producer: "Who would pick the MP mode of Prey 2 ahead of the one in for example Halo Reach? We'd rather to a really good SP adventure"
- There will be DLC
- There will be vag portals, but fewer of them and "with different looks"
- Loot system "similar to the one of Boarderlands"
- All the aliens look very human like, except for some of their limbs and obviously faces. Very similar to the Mass Effect aliens in both looks and armor/clothes, nothing like the Prey aliens.